Searchable abstracts of presentations at key conferences in endocrinology

ea0009p204 | Clinical | BES2005

Langerhans cell histiocytosis and auto-immune thyroiditis presenting as a thyroid mass with progressive hypothalamic-pituitary dysfunction

Deepak D , Woodcock B , MacFarlane I

A 53 year old woman developed a firm thyroid mass which was removed. The histology of the thyroid mass showed auto-immune thyroiditis and Langerhans cell Histiocytosis ( LCH). She also complained of thirst and polyuria. A water deprivation test confirmed cranial diabetes inspidus (CDI) ,the symptoms of which resolved on DDAVP . A glucagon stimulation test showed a blunted growth hormone (GH) response of 13.3 milliU per litre with an IGF-1 level of 16 nanomol per litre. The cor...